Aaron Berkowitz: Clinical Pathophysiology Made Ridiculously Simple (2007)

Teaches pathophysiology, mechanisms of disease and clinical reasoning hand-in-hand in a brief, clear, highly practical book for medical students preparing for the clinical years, nurses, nurse practitioners, physician assistants, and other health practitioners. Includes clinical cases and a CD-ROM (Mac/Win) teaching the differential diagnosis of common lab tests and patient symptoms and signs and the pathophysiological mechanisms behind the diagnoses. Excellent Board review (e.g. USMLE Step 1, NCLEX-RN). 195 pgs.; $29.95. (Sample pages: A, B, C)

ISBN10# 0940780801 ISBN13# 9780940780804

REVIEWS

"There are very few books that successfully walk the fine line between information overload and gross oversimplification. Berkowitz's Clinical Pathophysiology Made Ridiculously Simple manages to pull it off admirably well and will be a welcome change for scores of overwhelmed medical students."
David E. Newman-Toker, MD, Director, Student Clerkships in Neurology, Johns Hopkins University School of Medicine

"If you read one book during your preclinical years, read this! I've yet to come across a more clear and concise introduction to clinical pathophysiology. This book is a solid foundation for medical, nursing, and pharmacy students who want to understand human disease and treatments from first principles. I recommend it to anyone who aspires to take great care of their patients."
Andrew D. Levin, MD/PhD candidate, Harvard Medical School

"A thorough and insightful approach to basic pathophysiology, this book helps its readers develop a strong conceptual foundation of 'how' and 'why' disease happens, a skill that will far outlast memorization done for the boards and even provide a great review for residents and attending physicians."
Aarti Sekhar, MD, PGY-2, Radiology, Beth Israel Hospital

"This is absolutely brilliant -- things have never been more clear. It's everything you were supposed to learn in 1st year but didn't quite get, and everything in 2nd year you need for the boards. This is the most clear, well organized review text for the boards I've every seen!"
Jasmine Pedroso, 2nd Year Medical Student, UCLA Geffen School of Medicine

TABLE OF CONTENTS

CHAPTER 1. THE CARDIOVASCULAR SYSTEM
The Basic Circulation
Heart Failure
Diseases of the Heart Muscle: The Cardiomyopathies
The Valves and Their Diseases: Stenosis and Regurgitation
Diseases of the Electrical System: Arrhythmias
Diseases of the Heart's Vasculature: Angina and Myocardial Infarction
Vascular Disease Outside the Heart: Peripheral Arteries and Aorta
Lipids and Lipid-Lowering Drugs
Vasculitis
Hypertension
Cardiac Infection, Inflammation, and Neoplasia
Endocarditis
Rheumatic Fever and Rheumatic Heart Disease
Myocarditis
Pericarditis
Cardiac Neoplasia
Congenital Heart Disease

CHAPTER 2. THE PULMONARY SYSTEM
Micro-anatomical components of the pulmonary system: sac, membrane, and blood vessel
Obstructive and restrictive lung disease, and pulmonary function tests
Pulmonary physical exam
Pulmonary hypertension
Respiratory infections
Lung cancer
Diseases of the pleura and pleural space

CHAPTER 3. THE RENAL SYSTEM
Prerenal, intrinsic renal, and post-renal failure
Chronic renal failure
Urinary tract infection (UTI) and urinalysis
Tumors of the urinary tract
Fluids and electrolytes
--Hypernatremia and hyponatremia
--Hyperkalemia and hypokalemia
--Acid-base pathophysiology

CHAPTER 4. THE GASTROINTESTINAL SYSTEM
Diseases of the esophagus
Diseases of the stomach
Diseases of the small intestine
Diseases of the large Intestine
Upper and lower GI bleeding
Inflammatory bowel disease (IBD): Crohn's disease and ulcerative colitis
Diseases of the liver and gall bladder
Diseases of the pancreas
Approach to abdominal pain

CHAPTER 5. THE ENDOCRINE SYSTEM
General principles
Thyroid diseases
-- Hyperthyroidism
-- Hypothyroidism
-- Thyroiditis
-- Thyroid nodules and thyroid cancer
Adrenal gland
-- Cushing's syndrome
-- Adrenal insufficiency
-- Hyperaldosteronism and hypoaldosteronism
-- Multiple Endocrine Neoplasia (MEN)
Pituitary Gland
-- Diseases of the anterior pituitary
-- Diseases of the posterior pituitary
The endocrine pancreas and glucose regulation
-- Diabetes mellitus
-- Hypoglycemia
Calcium, the parathyroids, and bone
-- Hypercalcemia
-- Hypocalcemia
Diseases of bone
-- Osteopetrosis
-- Osteoporosis and osteomalacia
-- Paget's disease
-- Infection of bone: osteomyelitis
-- Tumors of bone

CHAPTER 6. THE HEMATOLOGIC SYSTEM
Red Blood Cells
-- Anemia
-- Polycythemia
White blood cells and immunology
--Hypersensitivity
--Immunodeficiency
--Hematologic malignancies
Platelets and the clotting cascade
-- Hypocoagulable states: tendency to bleed
-- Hypercoagulable states: tendency to clot

CHAPTER 7. THE NERVOUS SYSTEM
Review of neuroanatomy and introduction to localization
--Motor and sensory pathways
--Brainstem and cranial nerves
--Cerebellum and basal ganglia
Diseases of the brain
-- Mental status changes: dementia and delirium
-- Seizures
-- Elevated intracranial pressure
-- Intracranial infection and bleeding
-- CSF examination
-- CNS tumors
-- Stroke
-- Parkinson's disease
-- Multiple sclerosis
Diseases of the spinal cord
Diseases of lower motor neurons, neuromuscular junction, and muscle

CHAPTER 8. RHEUMATOLOGY
Rheumatologic disease
Treatment of autotoimmune diseases: Immunosuppressives and anti-inflammatories
Joint disease: arthritis
-- Rheumatoid arthritis
-- Osteoarthritis
-- Spondyloarthritis
-- Infectious arthritis
-- Gout and pseudogout

CHAPTER 9. MALE AND FEMALE REPRODUCTIVE SYSTEMS
Male reproductive organ pathophysiology
-- Prostate (prostatitis, benign prostatic hypertrophy, prostate cancer)
-- Testicles
-- Erectile dysfunction
Female reproductive organ pathophysiology
-- The menstrual cycle, oral contraceptives, and amenorrhea
-- Inflammation and infection of the female genital tract
-- Neoplasia of the female genital tract
-- Endometriosis
-- Polycystic ovary syndrome
Diseases of the breast
Infertility

CHAPTER 10. CLINICAL CASES

INDEX

DIFFERENTIAL DIAGNOSIS CD (MAC/WIN)
Differential Diagnosis of Common Laboratory Tests
Differential Diagnosis of Common Symptoms and Signs

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